The best ad network depends on your site type and results. In reality you need to check which is the best network for YOU. Google Ad Sense can be good for one site but bad for another. The issue here is try and see. There are others ad networks that might give more infromation like ad brite, and etc. (I can give you the full list if you like of most of the known companies). If you are a forum on a certain product (such ipod) you might need to check other sites that are more designated to this kind of product. All in all it is just depends on what is on your site...and your traction

Yep, exactly correct. For my sites I use Valueclick, Adsense and I am always trying something new. You will also find that the best network varies on the placement on your page, so try a few combinations out. You might check out pubmatic.com, I have been using their ad server and it is great for someone who is getting started with ads.

Do you know if any of the major ad networks will take ads for adult or otherwise NSFW sites?

Usually no, but there are ad networks and TONS of affiliate programs available to you.

This might seem like a strange question. We have made it so that it is very easy for one to click on our adsense ads by accident. Do you think google will block out account?Would they even notice?