In that timeframe it would by nature need to be capable of full self repair, with the shipped materials and energy, and with no wasted byproducts.
We'd have to completely re-think industrial processes. I'm in favor of realized nanotechnology and 3d printers at an atomic level. Evolution stumbled across carbon based lifeforms as it's answer on Earth.
Should be doable with beamed propulsion. Basically give each package a lightsail & you can have it maneuver when illuminated by laser arrays either in the home system or on the interstellar craft itself.
The beauty of this setup is that if you are really good at keeping the schedule, this can be all pre-computed. With time slots being allocated beforehand when the laser arrays send beams in a given direction & the packages (or the craft itself) just making really sure they stay in the beam & properly oriented when it arrives at the planed place and time.
We'd have to completely re-think industrial processes. I'm in favor of realized nanotechnology and 3d printers at an atomic level. Evolution stumbled across carbon based lifeforms as it's answer on Earth.