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> And nonsmoker cancers are a nontrivial proportion since they account for 10-25 percent of lung cancer worldwide, please just read the article.

I read the article, but I can't tell if there's a real problem or not. Having "nonsmokers accounts for 10% - 25% of lung cancer worldwide" doesn't leave me any wiser or more informed. Maybe I missed it in the article, so the rest of my comment is pointless, but ...

What's the percentage of lung cancer in nonsmokers? 10% of the pop? 1%? 0.00001%? Whatever the answer is, why isn't it in the article? Then we can see what "10% - 25% of $BASE_RATE" actually is. If we're seeing "10%-25% of 0.0001%", then that sorta tracks as fine, TBH.

The article seems almost designed to mislead: What's the base rate of lung cancer in nonsmokers? What's the base rate of lung cancer in smokers?

For example, if the base rate of lung cancer in smokers is 25% and the base rate of lung cancer in nonsmokers is 0.1%, then I don't see a problem here; funds directed to eliminating the remaining causes of lung cancer will be better spent on other research.

OTOH, if the base rate of lung cancer in smokers is 25% and the base rate of lung cancer in nonsmokers is %15, then I see a real problem here: maybe we need to direct more research funds towards lung cancer[1].

My expectation is that, with smoking so rare, lung cancer in the combined population must be very low, compared with the time when smoking was not rare.

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[1] Actually the problem is worse than that: if there was a singular cause for that 15% in my example, then we it would have been cheaper to target that cause instead of spending dollars reducing smoking.



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