We can take it one step further: There are microbes everywhere in your body, they matter and they do things. When you take them away or fuck with them too much, weird things start happening.
It is I think not a particularly surprising take. But then often it can be valuable to have things that are kind of obvious codified into a paper of some sort so that we no longer have to rely on "but isn't that obvious?" and can instead point to some primary source that actually explains what is true. That way it can be true for everyone, even the people for whom it wasn't already obvious.
The immune systems does nothing by accident. The immune system is always trying to keep the microbiome in balance and the microbiome helps the immune system as well.
It is I think not a particularly surprising take. But then often it can be valuable to have things that are kind of obvious codified into a paper of some sort so that we no longer have to rely on "but isn't that obvious?" and can instead point to some primary source that actually explains what is true. That way it can be true for everyone, even the people for whom it wasn't already obvious.