Roselle St (where Fabric8 Labs has their office) is the most innovative street in San Diego. I don't know what it is about that particular street, but a ton of great companies have come out of there.
Not a street I was aware of, but it's located between the Qualcomm and General Atomics campuses and a stones throw from UCSD. Also has great freeway and rail (commuter) access and modern research focussed buildings for lease.
