Have a look how games work. They are very performance critical - you have to calculate your simulation and draw it 60 times per second. That only works, if you have high performance low level libs. It is very common to mix C++ with lua. So yes, it is about balance, but it is standard procedure by now.

And with wasm (or even webGPU) one can do now the same with javascript and the web. Some logic in scripting is fine, but the heavy calculations should be lower level if one is aiming for performance.