Inflammation is an immunological reaction. It can be triggered a few different ways. Chronic inflammation is either because of a chronic infection or some sort of immune disorder. Chronic immune disorders don't just stop. They have a trigger and then keep going for the rest of the suffers life at some level. They can be controlled, but they can't be cured. This is because of the way the adaptive immune system works, which produces antibodies. Antibodies do a lot of different things, but one of the things they do is trigger inflammation in the presence of a specific protein. Your body has the capability of producing antibodies for basically any conceivable protein. Once an antibody is triggered, by having cell damage while the antibody is "activated." Your body replicates the B-cell that makes that specific antibody and the antibodies stick around in your blood stream. This is why you become "immune" after getting a vaccine, your body is able to "remember" the antibodies it needs to use in case you catch the real disease. When there is cell damage and the presence of another protein, your body could "remember" the wrong antibody. If it's environmental, this is an allergy. If it's from your own body, making the antibody attack some component of its own body, it's an autoimmune disorder. Once triggered, there's no known way to reverse that negative association. Immune disorders are also incredibly difficult to diagnose.
> When there is cell damage and the presence of another protein, your body could "remember" the wrong antibody.
I'm skeptical of this part. Aren't there always a huge number of proteins present in the body when cell damage occurs? For example, if I get a cold, and I eat chicken soup to prevent it, according to your explanation, I could develop antibodies for chicken soup. This doesn't seem to happen significantly often.
There are a lot of processes I skipped over. One of those is how the body removes B-Cells that react to benign or helpful proteins before they mature. But yes, if you had a B-Cell that produces antibodies against some antigen in Chicken soup, your scenario could lead to an allergy. The key is the body tries to select B-Cells that aren't going to produce antibodies that will be harmful to you. Sometimes it misses one and those are the ones that will cause an allergy or autoimmune disorder.
