> in which case it was evidence that administering male hormones may not produce the effect of natural ones.
The goal of trans hormone therapy is to reverse the effects of the hormones of the person's biological sex, so HRT dosage of e.g. testosterone is usually more than the average cis man would produce. It's possible that that much testosterone was too much for the person you mentioned to handle, especially for his body not being used to it, or that he just got prescribed for more than he should have taken. (He could've also gotten it from the black market, in which case it would almost definitely be an incorrect dosage.)
The goal of trans hormone therapy is to reverse the effects of the hormones of the person's biological sex, so HRT dosage of e.g. testosterone is usually more than the average cis man would produce. It's possible that that much testosterone was too much for the person you mentioned to handle, especially for his body not being used to it, or that he just got prescribed for more than he should have taken. (He could've also gotten it from the black market, in which case it would almost definitely be an incorrect dosage.)