I always thought it made sense that the improved efficiency comes at a cost. Our (human) kidneys are not as efficient, and we require a lot more water intake. Then again, we don't have as many kidney problems. This kind of argument certainly _feels_ right ("no free lunch"), but that does not necessarily make it so.
I feel that repeated inbreeding can (but does not have to) cause issues like sensitive kidneys in cats, but it probably also has to do with domestic cats growing relatively old. Things like faulty kidneys (or thyroid issues, or diabetes) bound to show up eventually if cancer does not get them before age 10.
I feel that repeated inbreeding can (but does not have to) cause issues like sensitive kidneys in cats, but it probably also has to do with domestic cats growing relatively old. Things like faulty kidneys (or thyroid issues, or diabetes) bound to show up eventually if cancer does not get them before age 10.