“Overall, current research suggests that vitamin C deficiency is associated with a higher risk of mortality from CVD and that vitamin C may slightly improve endothelial function and lipid profiles in some groups, especially those with low plasma vitamin C levels. However, the current literature provides little support for the widespread use of vitamin C supplementation to reduce CVD risk or mortality.”
Dr. Pauling theory does focus on L-ascorbic acid, but his unified theory relies on L-Lysine as well.
Not one published study that claims to refute Dr. Pauling's unified theory ever used the amount of L-ascorbic acid he recommended, or included L-lysine as part of the study. Dr. Pauling's unified theory has specific guideline amounts, as MG per KG of body weight for both L-ascorbic acid and L-lysine. It would be trivial to actually test Dr. Pauling's theory, but so far everyone has felt the need to alter his recommendations and then test their alteration and then claim victory.
It's easy to knock down a straw man, and even easier to revel in the success.
More than one of my Biochemistry professors lamented the fact that Pauling ruined his legacy with the Vitamin C obsession, but there is no evidence it worked.