I agree. To make a decent game an enormous mount of effort has to go into it. If you are a solo dev that has spent the last year pouring your heart into a game, I don't think $1000 to release it to a massive audience would stop it being published. If you employ a few people to create a higher quality game, compared to their wages, $1000 is nothing.

If you are a manga artist trying to release the 100th iteration of a 'game' based on suggestive images, it may slow you down.

Not suggesting that $1000 is the perfect price point, just that $100 is far too low.