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1.Lessons from 14 years at Google (addyosmani.com)
1665 points by cdrnsf 5 days ago | 689 comments
2.Gut bacteria from amphibians and reptiles achieve tumor elimination in mice (jaist.ac.jp)
498 points by Xunxi 22 days ago | 138 comments
3.Python Data Science Handbook (jakevdp.github.io)
312 points by cl3misch 38 days ago | 61 comments
4.S&box is now an open source game engine (sbox.game)
429 points by MaximilianEmel 44 days ago | 151 comments
5.Ask HN: Hearing aid wearers, what's hot?
356 points by pugworthy 46 days ago | 210 comments
6.AGI fantasy is a blocker to actual engineering (tomwphillips.co.uk)
632 points by tomwphillips 56 days ago | 647 comments
7.Game design is simple (raphkoster.com)
560 points by vrnvu 63 days ago | 173 comments
8.UPS plane crashes near Louisville airport (avherald.com)
421 points by jnsaff2 65 days ago | 438 comments
9.Attention lapses due to sleep deprivation due to flushing fluid from brain (news.mit.edu)
619 points by gmays 70 days ago | 291 comments
10.Doing well in your courses: Andrej's advice for success (2013) (stanford.edu)
680 points by peterkshultz 82 days ago | 198 comments
11.Talent (felixstocker.com)
242 points by BinaryIgor 85 days ago | 101 comments
12.A small number of samples can poison LLMs of any size (anthropic.com)
1202 points by meetpateltech 3 months ago | 439 comments
13.Legal Contracts Built for AI Agents (paid.ai)
72 points by arnon 3 months ago | 45 comments
14.Mod. 5140 - IBM's First Laptop Computer (richardsapperdesign.com)
80 points by jumpocelot 3 months ago | 42 comments
15.How to make sense of any mess (howtomakesenseofanymess.com)
462 points by surprisetalk 3 months ago | 140 comments
16.A history of ARM, part 1: Building the first chip (2022) (arstechnica.com)
118 points by ibobev 3 months ago | 26 comments
17.Getting AI to work in complex codebases (github.com/humanlayer)
517 points by dhorthy 3 months ago | 418 comments
18.The maths you need to start understanding LLMs (gilesthomas.com)
616 points by gpjt 4 months ago | 120 comments
19.PlasticList – Plastic Levels in Foods (plasticlist.org)
465 points by homebrewer 6 months ago | 193 comments
20.Design for 3D-Printing (rahix.de)
837 points by q3k 8 months ago | 210 comments
21.Tiny-LLM – a course of serving LLM on Apple Silicon for systems engineers (github.com/skyzh)
297 points by sarkory 8 months ago | 35 comments
22.Show HN: I built a hardware processor that runs Python (runpyxl.com)
983 points by hwpythonner 8 months ago | 265 comments
23.Show HN: I built an AI that turns GitHub codebases into easy tutorials (github.com/the-pocket)
923 points by zh2408 8 months ago | 172 comments
24.Underware 2.0 – Open Source Infinite Cable Management (makerworld.com)
223 points by reimertz 9 months ago | 67 comments
25.TL;DR of Deep Dive into LLMs Like ChatGPT by Andrej Karpathy (anfalmushtaq.com)
381 points by oleg_tarasov 11 months ago | 83 comments
26.DeepSeek-R1 (github.com/deepseek-ai)
1843 points by meetpateltech 11 months ago | 663 comments
27.Three-quarters of the land is drying out, 'redefining life on Earth' (grist.org)
146 points by rntn on Dec 25, 2024 | 105 comments
28.Cognitive load is what matters (minds.md)
1769 points by zdw on Dec 22, 2024 | 721 comments
29.Mitochondria Are Alive (asimov.press)
638 points by mailyk on Nov 8, 2024 | 389 comments
30.Maker Pipe – Structural Pipe Fittings for DIY Builders (makerpipe.com)
276 points by elsewhen on Sept 24, 2024 | 119 comments

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