Nah that’s an obvious one. Having unrelated health problems is a more important confunder (i.e. people with health problems, or old, or mentally ill, are mole likely to not drink).
People with health problems are told by their doctors to stop drinking alcohol.
From TFA:
"An analysis from 2007 by an international group of alcohol epidemiologists and addiction researchers, published in Annals of Epidemiology, notes that “as people progress into late middle and old age, their consumption of alcohol declines in tandem with ill health, frailty, dementia, and/or use of medications.” That decline means that, as people become less well—even if they’re not elderly—they will also tend to stop drinking."
I might have been too subtle since you TFA so nicely.
The article points to adverse health related events that cause abstainment. Clear and good the AoE-article works that out.
I however point out that it's pretty clear within the drinking categories you have effects that go in tandem with other illnesses as well (like self-medicating with alcohol for psychological issues).
So the whole argument they propose should at least be carried out to its full, working both ways. You've got illnesses moving people into abstainment and illnesses moving people into moderate or high alcohol usuage. The only way to control this is to use changes in comorbidity over time as a factor.
TBH the scientists in the underlying article write this down as an issue as well.
Right, I mis-summarized the article. A more accurate summary would be: non-drinkers are more likely to have pre-existing health problems than light-moderate drinkers.
Schizophrenia is basically symptoms of permeability of the blood brain barrier. Whole proteins pass through and mess things up. Similar to automimmune disease. Why else are those diseases on the list the only ones increasing in pravalence, and all others are decreasing (infectious, cancerous, viral, etc.). ASD is neuroprotective and tightens those cell junctions, with behavioral drawbacks. All these things are interrelated, the issue is they can be caused by 100k different contributing factors and susceptibilities.
If the diagnosis rate (incidence) increases, and people aren't dying rapidly, then the prevalence would surely increase as well. Unless you're using prevalence in the context of total people affected by a disease, regardless of whether or not they were diagnosed.
The penjulum of "things startups are wrong about" and/or "you succeed despite this rather than because of it" open plan offices will shift back the other way in the next decade to "deep work" and "closed door productivity". Joel Spolsky & co are just two decades ahead.
I went through and activated Google Authenticator 2FA for everything. I am at about 45% of all accounts now. If you want to send feedback to Namecheap: feedback@namecheap.com.
Senior individual sales, full-time, in person, 2000+ person company.
[07:30]: Wake up naturally. Shower, shave, get dressed.
[08:15]: Walk 5-minutes with wife to work for breakfast.
[08:30]: Standup over breakfast with team, very boring.
[09:00]: Start working on new business outreach. Phone meetings and remote demos all morning in succession in large open space full of around 40 desks. I like the energy of the environment. I occasionally book a room if I want some space to work but mostly like the intensity.
[12:00]: Catered company lunch with buddies and/or wife
[12:30]: More work, same as before except more existing deal outreach and internal meetings in afternoon. Mostly go to a breakout space to get things done, peak energy during this time. This part is the most fun generally.
[17:30]: Walk 5 minutes home with wife. Sometimes take the long way.
[18:00]: Start and eat dinner, go for a walk again or to the gym.
[20:00]: Work on side project for 1-2 hours if time allows.
[21:30]: Read nonfiction with wife for an hour or two before bed.
[23:00]: Head to bed and hang out chatting before dozing off.
I do this everyday and would not change a thing with the exception of removing all formal training and most internal meetings and adding kids. Same as when I had a company except the part about nonfiction, side projects and standups was just grinding away instead.
Socialization is for pets. I just ran around the forest and played Runescape for my single digit formative years. I did not learn to read until I was 11. To call my childhood homeschooling would be offensive (to me), school is the whole thing I was trying to avoid. I was home though. I played sports and chess with other people my age and older. I missed nothing but the cynicical, pluralistic burnout one gets attending school. And as an adult, I would not say I am missing anything social skills wise, other than that pathological desire to be normal school people have. Mimesis begets external validation begets emptiness.
I have done a great deal of armchair research in this area. It seems like if we can figure out a way to get the salt out of the cells, Salicornia protein would be an excellent, sustainable way to offer humans a plant based protein for which the inputs are literally sun and sea water and the output is a high quality vegan protein source that can be grown in the dessert. Getting the salt out of the cells was above my head biochem wise but I hope this goes the Tesla route of disruption, starting as a garnish on fancy hipster salads and ending up the standard in staple meal cooking greens. The biggest advantage is the lack of reliable on fresh water and ability to grow on saline land. If we can create the demand the business case for a business whose main inputs are sunlight and seawater is pretty strong.
